Description

Indicin CAS NO 480-82-0 is a pyrrolizidine alkaloid of significant interest in pharmaceutical and biochemical research. This natural product serves as a crucial intermediate and reference standard for the development of novel therapeutic agents and analytical methods. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in drug discovery, toxicology studies, and natural product chemistry.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for quality control and method validation in drug development and regulatory compliance.
• Biochemical Research: Serves as a key intermediate or substrate in enzymatic studies and metabolic pathway investigations related to pyrrolizidine alkaloids.
• Natural Product Isolation & Synthesis: Acts as a benchmark compound for the isolation, purification, and total synthesis of related alkaloids from plant sources.
• Toxicology & Safety Assessment: Employed in studies to understand the hepatotoxic mechanisms and metabolic activation of pyrrolizidine alkaloids.
• Analytical Method Development: Essential for developing and calibrating advanced analytical techniques such as HPLC, LC-MS, and NMR for alkaloid detection and quantification.
• Academic & Institutional Research: Used in universities and research institutes for pharmacological screening and chemical education.

Basic Information

Product Name	Indicin
CAS No.	480-82-0
Molecular Formula	C15H23NO5
Molecular Weight	297.35 g/mol
Synonyms	Indicine; (-)-Indicine; (7R,8R)-7-(2-Methylbutyryloxy)-1-methoxymethyl-1,2-dehydropyrrolizidine; Heliotridine 7-(2-methylbutanoate) 1-oxide; Lasiocarpine N-oxide; 1-Methoxymethyl-1,2-dehydro-7α-(2-methylbutyryloxy)-8α-hydroxypyrrolizidine N-oxide
EINECS	Contact for details

Quality Control

Our Indicin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications and research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.