Description

Resibufogenin is a bioactive bufadienolide compound derived from natural sources, known for its specific pharmacological properties. This high-purity chemical is critical for research and development in the life sciences, where precise molecular structure and consistent quality are paramount. It serves as a key reference standard and intermediate for pharmaceutical research, particularly in the study of cardiac glycosides and novel therapeutic agents. Global suppliers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors rely on this compound for its defined biological activity.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Biomedical Research: Serves as a crucial tool compound in pharmacological studies, especially for investigating Na+/K+-ATPase inhibition and related cardiac effects.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the synthesis and development of potential therapeutic agents targeting heart conditions.
• Analytical Chemistry: Utilized as a standard for HPLC, LC-MS, and other chromatographic techniques to identify and quantify related compounds in complex matrices.
• Biochemical Assay Development: Acts as a key component in developing high-throughput screening assays for drug discovery programs.
• Natural Product Chemistry: Used in the isolation, characterization, and study of other bufadienolides and related natural products.

Basic Information

Product Name	Resibufogenin
CAS No.	465-39-4
Molecular Formula	C24H32O4
Molecular Weight	384.51 g/mol
Synonyms	Resibufogenin; 14,15-Epoxy-3,5-dihydroxy-19-oxobufa-20,22-dienolide; 3β,5β-Dihydroxy-14β,15β-epoxybufa-20,22-dienolide; Bufogenin B; Arenobufagin; 465-39-4; NSC 526071
EINECS	Contact for details

Quality Control

Our Resibufogenin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR) and purity determination by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.