Description

(3R)-6,8A-Dimethyl-3-Propan-2-Yl-1,2,3,4,5,8-Hexahydroazulen-3A-Ol is a high-purity, complex sesquiterpene alcohol derivative valued for its unique stereochemistry and functional group. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), fragrance compounds, and specialty fine chemicals where precise stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in steroid and terpenoid-based drug discovery.
• Fragrance & Flavor Synthesis: Used as a precursor in the creation of complex, high-value aroma chemicals and natural product analogs for the perfumery and flavor industries.
• Organic Synthesis Research: Serves as a sophisticated building block in academic and industrial R&D for studying cyclization reactions, stereoselective transformations, and natural product total synthesis.
• Specialty Fine Chemicals: Employed in the production of catalysts, ligands, and other advanced materials where its specific azulene-derived structure imparts unique chemical properties.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(3R)-6,8A-Dimethyl-3-Propan-2-Yl-1,2,3,4,5,8-Hexahydroazulen-3A-Ol
CAS No.	465-28-1
Molecular Formula	C₁₅H₂₆O
Molecular Weight	222.37 g/mol
Synonyms	(3R)-3-Isopropyl-6,8a-dimethyl-1,2,3,4,5,8-hexahydroazulen-3a-ol; 3-Isopropyl-6,8a-dimethyl-1,2,3,4,5,8-hexahydroazulen-3a-ol; (3R)-6,8a-Dimethyl-3-(propan-2-yl)-1,2,3,4,5,8-hexahydroazulen-3a-ol; Hexahydroazulenol derivative; Sesquiterpene alcohol intermediate
EINECS	Contact for details

Quality Control

Every batch of (3R)-6,8A-Dimethyl-3-Propan-2-Yl-1,2,3,4,5,8-Hexahydroazulen-3A-Ol is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the container has been opened.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.