Description

Piperazine, 1-(3-Fluoropropyl)- (9Ci) is a specialized fluorinated piperazine derivative, a key building block in modern organic synthesis. Its value lies in the strategic incorporation of a fluorine atom, which can significantly alter the physicochemical and metabolic properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where the fluoropropyl-piperazine moiety serves as a crucial pharmacophore or structural modifier.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its nitrogen donor atoms and fluorinated side chain.
• Chemical Biology Probe: Acts as a building block for creating molecular probes to study biological pathways and protein interactions.
• Material Science Research: Utilized in the synthesis of specialty polymers and advanced materials with tailored surface properties.

Basic Information

Product Name	Piperazine, 1-(3-Fluoropropyl)- (9Ci)
CAS No.	399580-57-5
Molecular Formula	C7H15FN2
Molecular Weight	146.21 g/mol
Synonyms	1-(3-Fluoropropyl)piperazine; N-(3-Fluoropropyl)piperazine; 3-Fluoropropyl-piperazine; Piperazine, N-(3-fluoropropyl)-; 399580-57-5; 1-(3-Fluoropropyl)piperazine (9CI); N-(3-Fluoropropyl)piperazine (9CI)
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(3-Fluoropropyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and cGMP manufacturing needs with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.