Description

2-Piperazineacetic Acid, 5-(Mercaptomethyl)-3,6-Dioxo- (9Ci) is a specialized heterocyclic building block featuring a piperazine core with acetic acid and thiol functionalities. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially those targeting neurological or metabolic pathways.
• Ligand Synthesis for Catalysis: Used to create novel chelating ligands for metal-catalyzed reactions due to its nitrogen and sulfur donor atoms.
• Peptidomimetic Research: Acts as a constrained scaffold or a functionalized amino acid analog in the design of peptide-like molecules.
• Agrochemical Active Ingredient Development: Employed in the research phase for creating new herbicides or fungicides.
• Bioconjugation Chemistry: The thiol (mercapto) group enables site-specific conjugation to proteins, antibodies, or other biomolecules for diagnostic or therapeutic applications.
• Material Science Research: Investigated as a monomer or cross-linker for developing novel polymers with specific functional properties.

Basic Information

Product Name	2-Piperazineacetic Acid, 5-(Mercaptomethyl)-3,6-Dioxo- (9Ci)
CAS No.	397847-74-4
Molecular Formula	C7H10N2O4S
Molecular Weight	218.23 g/mol
Synonyms	5-(Mercaptomethyl)-3,6-dioxo-2-piperazineacetic acid; 2-Piperazineacetic acid, 5-(mercaptomethyl)-3,6-dioxo-; 5-(Mercaptomethyl)-3,6-dioxopiperazine-2-acetic acid; (5-Mercaptomethyl-3,6-dioxopiperazin-2-yl)acetic acid; 2,5-Diketopiperazine-2-acetic acid derivative; Thiol-functionalized Diketopiperazine Acetic Acid; DKP-Acetic Acid Thiol Derivative
EINECS	Contact for details

Quality Control

Our 2-Piperazineacetic Acid, 5-(Mercaptomethyl)-3,6-Dioxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation of the thiol group and maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.