Description

2-Piperazineacetic Acid, 5-(1-Hydroxyethyl)-3,6-Dioxo- (9Ci) is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique piperazine-dione core functionalized with acetic acid and hydroxyethyl groups, enabling its use in constructing complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in classes targeting neurological or metabolic disorders.
• Agrochemical Synthesis: Used in the creation of advanced, high-efficacy pesticide and herbicide molecules.
• Chemical Biology Probe Development: Serves as a versatile scaffold for designing enzyme inhibitors or receptor ligands in biochemical research.
• Peptidomimetic Chemistry: The piperazine-dione structure mimics peptide bonds, making it valuable for creating stable peptide analogs with modified properties.
• Ligand and Catalyst Development: Potential use in designing novel chelating ligands for metal catalysis or separation sciences.
• Academic & Institutional Research: Employed in universities and R&D institutes for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Piperazineacetic Acid, 5-(1-Hydroxyethyl)-3,6-Dioxo- (9Ci)
CAS No.	397847-55-1
Molecular Formula	C8H12N2O5
Molecular Weight	216.19 g/mol
Synonyms	5-(1-Hydroxyethyl)-3,6-dioxopiperazine-2-acetic acid; (5S)-5-(1-Hydroxyethyl)-3,6-dioxopiperazine-2-acetic acid; 2-Piperazineacetic acid, 5-(1-hydroxyethyl)-3,6-dioxo-; L-α-(5-(1-Hydroxyethyl)-2,5-diketopiperazin-1-yl)acetic acid; 1-[(Carboxymethyl)-5-[(1S)-1-hydroxyethyl]-2,6-dioxopiperazine; A potential metabolite or derivative of certain β-lactam antibiotics.
EINECS	Contact for details

Quality Control

Every batch of 2-Piperazineacetic Acid, 5-(1-Hydroxyethyl)-3,6-Dioxo- (9Ci) is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.