Description

2-Piperazineacetic Acid, 5-(1-Methylethyl)-3,6-Dioxo- (9Ci) is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its unique piperazine-dione core structure makes it a valuable intermediate for constructing complex molecules with potential biological activity. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing protease inhibitor activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Peptidomimetic Chemistry: Acts as a constrained dipeptide surrogate or a conformationally restricted scaffold in the design of peptide mimics for therapeutic applications.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized chelating ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Academic & Contract Research: A critical reagent for synthetic methodology development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals beyond the life sciences sector.

Basic Information

Product Name	2-Piperazineacetic Acid, 5-(1-Methylethyl)-3,6-Dioxo- (9Ci)
CAS No.	397847-48-2
Molecular Formula	C9H14N2O4
Molecular Weight	214.22 g/mol
Synonyms	5-Isopropyl-2,5-diazabicyclo[2.2.2]octane-3,6-dione-2-acetic acid; 5-Isopropyl-3,6-dioxopiperazine-2-acetic acid; 2-(5-Isopropyl-3,6-dioxopiperazin-2-yl)acetic acid; 5-(1-Methylethyl)-3,6-dioxo-2-piperazineacetic acid; (5-Isopropyl-3,6-dioxopiperazin-2-yl)acetic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Piperazineacetic Acid, 5-(1-Methylethyl)-3,6-Dioxo- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) including results from HPLC, NMR, and mass spectrometry is supplied with each shipment to guarantee it meets your specific research-grade or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.