Description

2-Piperazineaceticacid,5-Methyl-3,6-Dioxo-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to create complex target structures for drug discovery programs. Its defined stereochemistry and functional groups make it a valuable scaffold for constructing libraries of bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used in high-throughput screening and combinatorial chemistry to develop new drug candidates and explore structure-activity relationships (SAR).
• Protease Inhibitor Development: Acts as a core scaffold or side-chain component in the design and synthesis of protease inhibitors due to its piperazine-acetic acid structure.
• Peptidomimetic Synthesis: Employed in the creation of peptidomimetics, where it can mimic natural peptide structures to enhance stability and bioavailability.
• Ligand Synthesis for Receptor Studies: Utilized to synthesize specific ligands for pharmacological characterization of G-protein coupled receptors (GPCRs) and other biological targets.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and cellular pathways in biochemical research.

Basic Information

Product Name	2-Piperazineaceticacid,5-Methyl-3,6-Dioxo-(9Ci)
CAS No.	397847-46-0
Molecular Formula	C7H10N2O3
Molecular Weight	170.17 g/mol
Synonyms	5-Methyl-3,6-dioxopiperazine-2-acetic acid; 2-(5-Methyl-3,6-dioxopiperazin-2-yl)acetic acid; 5-Methyl-3,6-dioxopiperazineacetic acid; (5-Methyl-3,6-dioxopiperazin-2-yl)acetic acid; 2-Piperazineacetic acid, 5-methyl-3,6-dioxo-; 397847-46-0; 5-Methyl-3,6-dioxo-2-piperazineacetic acid
EINECS	Contact for details

Quality Control

Our 2-Piperazineaceticacid,5-Methyl-3,6-Dioxo-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.