Description

1-tert-Butyl 4-Ethyl 4-(Phenylthio)Piperidine-1,4-Dicarboxylate is a high-purity, synthetic organic compound belonging to the piperidine dicarboxylate class, serving as a critical advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis. Its unique structure, featuring a tert-butyl and ethyl ester group alongside a phenylthio moiety, makes it an essential precursor for the development of complex, biologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Organic Synthesis Reagent: Used in multi-step synthetic routes to construct complex heterocyclic frameworks and functionalized piperidine derivatives.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for method development and exploration of new chemical spaces.
• Agrochemical Synthesis: Potential intermediate in the development of new active ingredients for crop protection products.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced functional materials.

Basic Information

Product Name	1-tert-Butyl 4-Ethyl 4-(Phenylthio)Piperidine-1,4-Dicarboxylate
CAS No.	397264-09-4
Molecular Formula	C19H27NO4S
Molecular Weight	365.49 g/mol
Synonyms	1-tert-Butyl 4-ethyl 4-(phenylsulfanyl)piperidine-1,4-dicarboxylate; 4-(Phenylthio)-1,4-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 4-ethyl ester; 4-Ethyl 1-tert-butyl 4-(phenylthio)piperidine-1,4-dicarboxylate; tert-Butyl ethyl 4-(phenylthio)piperidine-1,4-dicarboxylate; 397264-09-4; 1-Boc-4-(phenylthio)-4-(ethoxycarbonyl)piperidine; 4-(Ethoxycarbonyl)-4-(phenylthio)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of 1-tert-Butyl 4-Ethyl 4-(Phenylthio)Piperidine-1,4-Dicarboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0% (Area %)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.