Description

Pyrazino[1,2-A]Indole, 6-Ethyl-1,2,3,4,10,10A-Hexahydro-4-Methyl-, (4R,10Ar)- (9Ci) is a complex, stereochemically defined heterocyclic compound belonging to the pyrazinoindole class. This high-purity intermediate is of significant value in advanced pharmaceutical research and development, particularly for its potential role in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of complex drug candidates, especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new molecules with targeted biological activity.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale, requiring consistent high purity and stereochemical integrity.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in API manufacturing.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its defined stereochemistry at the 4R and 10Ar positions, enabling the construction of enantiomerically pure compounds.

Basic Information

Product Name	Pyrazino[1,2-A]Indole, 6-Ethyl-1,2,3,4,10,10A-Hexahydro-4-Methyl-, (4R,10Ar)- (9Ci)
CAS No.	396074-62-7
Molecular Formula	C15H20N2
Molecular Weight	228.33 g/mol
Synonyms	(4R,10aR)-6-Ethyl-4-methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indole; 6-Ethyl-1,2,3,4,10,10a-hexahydro-4-methyl-pyrazino[1,2-a]indole, (4R,10aR)-; (4R,10aR)-6-Ethyl-4-methyl-2,3,4,10-tetrahydropyrazino[1,2-a]indole; Hexahydropyrazinoindole derivative; Chiral Pyrazinoindole Intermediate; CAS 396074-62-7
EINECS	Contact for details

Quality Control

Our Pyrazino[1,2-A]Indole derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC, NMR, and mass spectrometry, to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.