Description

Imrecoxib is a highly selective and potent non-steroidal anti-inflammatory drug (NSAID) belonging to the coxib class, specifically designed as a cyclooxygenase-2 (COX-2) inhibitor. This compound is of significant commercial and research interest for its targeted mechanism of action, which aims to provide effective analgesia and anti-inflammatory benefits while minimizing the gastrointestinal side effects associated with traditional NSAIDs. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of novel therapeutic agents for pain management, osteoarthritis, and rheumatoid arthritis.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of prescription medications for chronic pain and inflammation.
• Clinical Research & Development: Critical reference standard and intermediate in preclinical and clinical studies for new COX-2 inhibitor drugs.
• Analytical Standard: High-purity material used for method development, validation, and quality control testing in analytical laboratories.
• Academic & Biomedical Research: Tool compound for investigating COX-2 enzyme pathways, inflammatory processes, and related disease models.
• Generic Drug Manufacturing: Serves as the key API for companies developing bioequivalent versions of established coxib-based therapies.

Basic Information

Product Name	Imrecoxib
CAS No.	395683-14-4
Molecular Formula	C16H14N2O3S
Molecular Weight	314.36 g/mol
Synonyms	4-(4-Methylsulfonylphenyl)-3-phenyl-5H-furan-2-one; BAP-909; Imrecoxibum; COX-2 Inhibitor BAP-909; UNII-6V9R0R4H4S; 3-Phenyl-4-(4-(methylsulfonyl)phenyl)-2(5H)-furanone; 2(5H)-Furanone, 3-phenyl-4-[4-(methylsulfonyl)phenyl]-
EINECS	Contact for details

Quality Control

Our Imrecoxib is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting full compliance with in-house specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.