Description

3-Amino-2-Piperazin-1-Ylbenzoic Acid is a high-purity, functionalized benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a piperazinyl substituent, makes it a versatile intermediate for constructing complex molecules with specific biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists to explore structure-activity relationships (SAR) and develop new chemical entities.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis or metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty dyes, pigments, and advanced materials.
• Bioconjugation Chemistry: The amino and carboxylic acid functional groups allow for its use in linking molecules, useful in probe or conjugate development.

Basic Information

Product Name	3-Amino-2-Piperazin-1-Ylbenzoic Acid
CAS No.	394655-10-8
Molecular Formula	C11H16N4O2
Molecular Weight	236.27 g/mol
Synonyms	2-(Piperazin-1-yl)-3-aminobenzoic Acid; 3-Amino-2-(1-piperazinyl)benzoic Acid; Benzoic acid, 3-amino-2-(1-piperazinyl)-; 394655-10-8; 3-Amino-2-piperazin-1-yl-benzoic acid; 2-Piperazin-1-yl-3-aminobenzoic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Piperazin-1-Ylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.