Description

tert-Butyl 4-(4-Amino-2-Methoxyphenyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive amine handle for constructing complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• API Synthesis: Serves as a core scaffold for constructing complex molecules in the development of new Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Used in the research and development of new herbicides, fungicides, and insecticides that utilize piperazine-based chemistries.
• Chemical Biology & Proteomics: Employed as a linker or spacer molecule in the design of chemical probes and bioconjugates for target identification and validation.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with specific functional properties.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences sector.

Basic Information

Product Name	tert-Butyl 4-(4-Amino-2-Methoxyphenyl)Piperazine-1-Carboxylate
CAS No.	394249-00-4
Molecular Formula	C16H25N3O3
Molecular Weight	307.39 g/mol
Synonyms	1-Boc-4-(4-Amino-2-methoxyphenyl)piperazine; tert-Butyl 4-(4-amino-2-methoxyphenyl)-1-piperazinecarboxylate; 4-(4-Amino-2-methoxyphenyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(4-amino-2-methoxyphenyl)piperazine; BOC-4-(4-Amino-2-Methoxyphenyl)Piperazine; 394249-00-4; N-Boc-4-(4-amino-2-methoxyphenyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Amino-2-Methoxyphenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.