Description

(3R)-1-(3-Chloropyridin-2-Yl)-3-Methylpiperazine is a high-purity chiral piperazine derivative and a key synthetic intermediate in modern pharmaceutical development. This compound matters for its critical role in constructing complex molecules with specific stereochemistry, enabling the production of targeted active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of advanced drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its heterocyclic structure.
• Chemical Synthesis: Serves as a versatile chiral ligand or precursor in asymmetric synthesis and catalysis for fine chemical production.
• Academic & R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	(3R)-1-(3-Chloropyridin-2-Yl)-3-Methylpiperazine
CAS No.	393513-95-6
Molecular Formula	C10H14ClN3
Molecular Weight	211.69 g/mol
Synonyms	(R)-1-(3-Chloro-2-pyridinyl)-3-methylpiperazine; (3R)-1-(3-Chloropyridin-2-yl)-3-methylpiperazine; 3-Methyl-1-(3-chloro-2-pyridinyl)piperazine, (3R)-; 393513-95-6; (R)-3-Methyl-1-(3-chloro-2-pyridinyl)piperazine; 1-(3-Chloro-2-pyridinyl)-3-methyl-(R)-piperazine; (R)-1-(3-Chloro-pyridin-2-yl)-3-methyl-piperazine
EINECS	Contact for details

Quality Control

Our (3R)-1-(3-Chloropyridin-2-Yl)-3-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.