Description

tert-Butyl 4-(3-Nitrobenzoyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific functional groups. This compound is of significant value in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, where its structure serves as a key building block. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or other therapeutic areas.
• Peptidomimetic Research: Used in the design and development of peptidomimetics and constrained peptide analogs due to its tetrahydro-1(2H)-pyrazinecarboxylate scaffold.
• Agrochemical Synthesis: Serves as a building block for creating new molecules with potential herbicidal or insecticidal activity.
• Chemical Biology Probes: Employed in the construction of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	tert-Butyl 4-(3-Nitrobenzoyl)Tetrahydro-1(2H)-Pyrazinecarboxylate
CAS No.	389628-56-2
Molecular Formula	C16H21N3O5
Molecular Weight	335.36 g/mol
Synonyms	1-Boc-4-(3-nitrobenzoyl)piperazine; tert-Butyl 4-(3-nitrobenzoyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(3-nitrobenzoyl)piperazine; 4-(3-Nitrobenzoyl)piperazine-1-carboxylic acid tert-butyl ester; 389628-56-2; 1-Boc-4-(3-nitrobenzoyl)piperazine; 1-N-Boc-4-(3-nitrobenzoyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Nitrobenzoyl)Tetrahydro-1(2H)-Pyrazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.