Description

2-{4-[(4-Methylphenyl)Sulfonyl]-1-Piperazinyl}-N'-[(1-Methyl-1H-Pyrrol-2-Yl)Methylene]Acetohydrazide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research targeting central nervous system and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates, especially those with piperazine and pyrrole pharmacophores.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of specialized compounds for client projects.
• Biochemical Research: May be utilized in the development of chemical probes or tool compounds for investigating biological pathways and target validation.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-{4-[(4-Methylphenyl)Sulfonyl]-1-Piperazinyl}-N'-[(1-Methyl-1H-Pyrrol-2-Yl)Methylene]Acetohydrazide
CAS No.	385404-33-1
Molecular Formula	C19H25N5O3S
Molecular Weight	403.50 g/mol
Synonyms	2-[4-(4-Tolylsulfonyl)piperazin-1-yl]-N'-[(1-methyl-1H-pyrrol-2-yl)methylidene]acetohydrazide; 2-(4-(p-Tolylsulfonyl)piperazin-1-yl)-N'-((1-methyl-1H-pyrrol-2-yl)methylene)acetohydrazide; 385404-33-1; Acetohydrazide, 2-[4-[(4-methylphenyl)sulfonyl]-1-piperazinyl]-N'-[(1-methyl-1H-pyrrol-2-yl)methylene]-; Tosylpiperazine acetohydrazide derivative
EINECS	Contact for details

Quality Control

Our 2-{4-[(4-Methylphenyl)Sulfonyl]-1-Piperazinyl}-N'-[(1-Methyl-1H-Pyrrol-2-Yl)Methylene]Acetohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.