Description

Piperazine, 1-Ethyl-4-[(4-Nitrophenyl)Sulfonyl]- is a specialized piperazine derivative featuring a sulfonyl linker and a nitroaryl group, making it a valuable synthetic intermediate for constructing complex molecular architectures. Its core value lies in its role as a key building block in the development of active pharmaceutical ingredients (APIs) and advanced organic materials, where precise chemical functionality is paramount. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific sulfonamide and aryl motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, or as kinase inhibitors.
• Agrochemical Research: Used in developing new herbicides, fungicides, or insecticides where the piperazine-sulfonyl scaffold can contribute to biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, dyes, or photoactive materials.
• Chemical Biology Probes: Utilized in creating labeled compounds or probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Piperazine, 1-Ethyl-4-[(4-Nitrophenyl)Sulfonyl]-
CAS No.	385403-85-0
Molecular Formula	C12H17N3O4S
Molecular Weight	299.35 g/mol
Synonyms	1-Ethyl-4-[(4-nitrophenyl)sulfonyl]piperazine; 4-Nitro-N-(1-ethylpiperazin-4-yl)benzenesulfonamide; N-(1-Ethylpiperazin-4-yl)-4-nitrobenzenesulfonamide; 1-Ethyl-4-(4-nitrobenzenesulfonyl)piperazine; 4-Nitrobenzenesulfonic acid 1-ethylpiperazin-4-ylamide
EINECS	Contact for details

Quality Control

Our Piperazine, 1-Ethyl-4-[(4-Nitrophenyl)Sulfonyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance (including REACH) ensures a reliable supply for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.