Description

Total Ganglioside Extract (Brain, Porcine-Ammonium Salt) is a complex mixture of glycosphingolipids, specifically gangliosides, sourced from porcine brain tissue and presented as an ammonium salt. This extract is a critical biochemical reagent valued for its role in neuroscience research, cell signaling studies, and as a reference standard. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity, biologically active lipid components for advanced studies in neurobiology, membrane structure, and glycosphingolipid metabolism.

Application

• Neuroscience Research: Used as a key reagent in studying neuronal cell membranes, synaptic function, and neurodegenerative disease models.
• Biochemical Standard: Serves as a reference material for the identification and quantification of ganglioside species via techniques like TLC, HPLC, and mass spectrometry.
• Cell Biology Studies: Employed to investigate the role of gangliosides in cell signaling, proliferation, and differentiation processes.
• Pharmaceutical Development: Acts as a starting material or intermediate in the research and development of neuroactive compounds and potential therapeutics.
• Diagnostic Reagent Manufacturing: Utilized in the production of components for diagnostic kits targeting neurological markers.
• Academic & Institutional Research: A fundamental tool for universities and research institutes conducting fundamental studies on glycolipid biochemistry.

Basic Information

Product Name	Total Ganglioside Extract (Brain, Porcine-Ammonium Salt)
CAS No.	383907-71-9
Molecular Formula	Mixture
Molecular Weight	Mixture
Synonyms	Ganglioside Mixture (Porcine Brain); Porcine Brain Gangliosides; Brain Gangliosides, Ammonium Salt; Ganglioside Extract; Glycosphingolipid Extract; GM1/GD1a/GT1b Mixture; Svennerholm Ganglioside Mixture; Ganglioside Ammonium Salt
EINECS	Contact for details

Quality Control

Our Total Ganglioside Extract is produced under stringent quality management protocols. Each batch is characterized to ensure consistency in ganglioside profile and biological activity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specifications such as ganglioside composition, purity, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (TLC)	Conforms to standard ganglioside profile (GM1, GD1a, GD1b, GT1b)
Assay (Total Ganglioside, as Sialic Acid)	≥95% (by HPLC or colorimetric method)
Solubility	Soluble in chloroform/methanol/water mixtures
Loss on Drying	≤5.0%
Residual Solvents	Meets ICH guidelines
Bacterial Endotoxins	<1.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.