Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-7-[4-(2-Furanylcarbonyl)-1-Piperazinyl]-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of novel fluoroquinolone antibiotics, offering a key structural motif for developing potent antimicrobial agents. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of next-generation antibacterial therapies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel fluoroquinolone antibiotic candidates.
• Antimicrobial Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new antibacterial agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the R&D pipeline for new antibiotic APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for pharmacological and microbiological studies.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-7-[4-(2-Furanylcarbonyl)-1-Piperazinyl]-1,4-Dihydro-4-Oxo-
CAS No.	383902-78-1
Molecular Formula	C20H18FN3O4
Molecular Weight	383.38 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-[4-(2-furoyl)piperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(2-furoyl)-1-piperazinyl)-3-quinolinecarboxylic acid; 7-[4-(2-Furoyl)-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; Garenoxacin Intermediate; Garenoxacin Quinoline Core; AM-1155 Intermediate; T-3811 Intermediate; BMS-284756 Intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is sensitive to light (store away from light) and may be incompatible with strong alkalis and fluorides. Keep away from heat and ignition sources.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.