Description

5-(2-Pyrazinyl)-1,3,4-Thiadiazol-2-Amine is a high-purity heterocyclic organic compound featuring a fused pyrazine and 1,3,4-thiadiazole core structure. This specialized chemical building block is valued for its unique electronic properties and reactivity, making it a critical intermediate in advanced synthetic chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and corrosion inhibitors due to its electron-rich structure.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex nitrogen- and sulfur-containing heterocycles.
• Bioconjugation & Probe Development: Utilized in the design of fluorescent probes and biochemical tools where its amine group allows for specific conjugation.

Basic Information

Product Name	5-(2-Pyrazinyl)-1,3,4-Thiadiazol-2-Amine
CAS No.	383130-62-9
Molecular Formula	C6H5N5S
Molecular Weight	179.21 g/mol
Synonyms	2-Amino-5-(pyrazin-2-yl)-1,3,4-thiadiazole; 5-(Pyrazin-2-yl)-1,3,4-thiadiazol-2-amine; 2-Pyrazinyl-1,3,4-thiadiazol-5-amine; 1,3,4-Thiadiazol-2-amine, 5-(2-pyrazinyl)-; 5-(2-Pyrazinyl)-2-amino-1,3,4-thiadiazole; 2-Amino-5-(2-pyrazinyl)-1,3,4-thiadiazole
EINECS	Contact for details

Quality Control

Our 5-(2-Pyrazinyl)-1,3,4-Thiadiazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.