Description

1-(4-Nitro-2-Trifluoromethylphenyl)-Piperazine is a high-value, multi-functional chemical intermediate featuring a unique trifluoromethylphenyl-piperazine scaffold. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical candidates and agrochemicals, where its specific substitution pattern imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, leveraging the bioactivity of the trifluoromethyl and nitro groups.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for catalytic systems or as a component in advanced material synthesis.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-(4-Nitro-2-Trifluoromethylphenyl)-Piperazine
CAS No.	381242-61-1
Molecular Formula	C11H12F3N3O2
Molecular Weight	275.23 g/mol
Synonyms	1-(4-Nitro-2-(trifluoromethyl)phenyl)piperazine; 4-Nitro-2-(trifluoromethyl)phenylpiperazine; 2-Trifluoromethyl-4-nitrophenylpiperazine; 1-(2-Trifluoromethyl-4-nitrophenyl)piperazine; Piperazine, 1-[4-nitro-2-(trifluoromethyl)phenyl]-; 381242-61-1; 4-Nitro-α,α,α-trifluoro-o-toluidine, N-piperazinyl derivative
EINECS	Contact for details

Quality Control

Our 1-(4-Nitro-2-Trifluoromethylphenyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.