Description

2-(4-(Trifluoromethyl)Phenyl)Pyrazine is a specialized heterocyclic aromatic compound featuring a pyrazine ring linked to a trifluoromethyl-substituted phenyl group. This molecular architecture, particularly the presence of the electron-withdrawing trifluoromethyl group, makes it a valuable and versatile building block in advanced organic synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas like kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Serves as a core structure for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of organic electronic materials, such as ligands for OLEDs and components for conductive polymers.
• Ligand and Catalyst Design: The pyrazine moiety acts as a coordinating unit in the synthesis of complex catalysts for asymmetric synthesis and other catalytic processes.
• Fluorinated Compound Library: An essential substrate for building diverse fluorinated compound libraries used in high-throughput screening for biological activity.

Basic Information

Product Name	2-(4-(Trifluoromethyl)Phenyl)Pyrazine
CAS No.	380626-88-0
Molecular Formula	C11H7F3N2
Molecular Weight	224.19 g/mol
Synonyms	2-[4-(Trifluoromethyl)phenyl]pyrazine; 4-(Pyrazin-2-yl)benzotrifluoride; 2-(4-Trifluoromethylphenyl)pyrazine; 2-(alpha,alpha,α-Trifluoro-p-tolyl)pyrazine; Pyrazine, 2-[4-(trifluoromethyl)phenyl]-; 380626-88-0; 2-(4-Trifluoromethylphenyl)pyrazine
EINECS	Contact for details

Quality Control

Every batch of 2-(4-(Trifluoromethyl)Phenyl)Pyrazine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.