Description

3-[4-(2-Fluoro-Phenyl)-Piperazin-1-Yl]-3-Oxo-Propionitrile is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly within medicinal chemistry research. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic compounds and piperazine derivatives.
• Contract Research & Development: Supplied to CROs and CDMOs for custom synthesis projects and process development.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in API manufacturing.
• Biochemical Research: Investigated for its interaction with various biological targets in early-stage discovery programs.

Basic Information

Item	Detail
Product Name	3-[4-(2-Fluoro-Phenyl)-Piperazin-1-Yl]-3-Oxo-Propionitrile
CAS No.	379726-07-5
Molecular Formula	C13H14FN3O
Molecular Weight	247.27 g/mol
Synonyms	2-Cyano-1-[4-(2-fluorophenyl)piperazin-1-yl]ethanone; 1-[4-(2-Fluorophenyl)piperazin-1-yl]-2-oxo-2-cyanoethane; 3-Oxo-3-[4-(2-fluorophenyl)-1-piperazinyl]propanenitrile; (2-Fluorophenyl)piperazine propanenitrile derivative; FPPOP; 379726-07-5; 3-[4-(2-Fluorophenyl)piperazin-1-yl]-3-oxopropanenitrile
EINECS	Contact for details

Quality Control

Our 3-[4-(2-Fluoro-Phenyl)-Piperazin-1-Yl]-3-Oxo-Propionitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.