Description

2-Piperidinecarboxylic Acid, 1-(Chlorocarbonyl)-, Methyl Ester, (2S)- (9Ci) is a high-purity chiral building block and key synthetic intermediate. This compound is critical for the development of active pharmaceutical ingredients (APIs) and fine chemicals, where stereochemical control is paramount. It is primarily required by pharmaceutical R&D laboratories, custom synthesis facilities, and manufacturers of advanced agrochemicals and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the research and production of advanced, optically active pesticides and herbicides.
• Peptidomimetics & Protease Inhibitors: Serves as a constrained amino acid analog for constructing peptide-like structures in medicinal chemistry.
• Catalyst & Ligand Preparation: Employed in the development of novel chiral catalysts and ligands for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis and scale-up projects.
• Academic & Industrial Research: Utilized in chemical research for exploring new synthetic methodologies and bioactive compounds.

Basic Information

Product Name	2-Piperidinecarboxylic Acid, 1-(Chlorocarbonyl)-, Methyl Ester, (2S)- (9Ci)
CAS No.	376347-06-7
Molecular Formula	C8H12ClNO3
Molecular Weight	205.64 g/mol
Synonyms	(2S)-1-(Chlorocarbonyl)piperidine-2-carboxylic acid methyl ester; Methyl (2S)-1-(chlorocarbonyl)piperidine-2-carboxylate; L-Pipecolic acid, 1-(chlorocarbonyl)-, methyl ester; (S)-1-(Chlorocarbonyl)piperidine-2-carboxylic acid methyl ester; 1-Carboxy-2-piperidinecarboxylic acid methyl ester chloride; 376347-06-7; (2S)-1-(Chlorocarbonyl)-2-piperidinecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of 2-Piperidinecarboxylic Acid, 1-(Chlorocarbonyl)-, Methyl Ester, (2S)- (9Ci) adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.