Description

tert-Butyl 5,6-Dihydroimidazo[1,5-A]Pyrazine-7(8H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a fused imidazopyrazine heterocyclic core protected by a tert-butoxycarbonyl (Boc) group. This compound is critical for the synthesis of complex bioactive molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel therapeutics, including kinase inhibitors and other small-molecule drugs targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop novel drug candidates.
• Kinase Inhibitor Synthesis: Serves as a core scaffold or precursor for compounds targeting specific kinase enzymes involved in cancer and inflammatory diseases.
• Process Chemistry Development: Employed in route scouting and scale-up processes for the commercial manufacturing of targeted therapies.
• Bioconjugation & Probe Development: The Boc-protected amine provides a handle for further functionalization, useful in creating chemical probes for biological assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D and production.

Basic Information

Product Name	tert-Butyl 5,6-Dihydroimidazo[1,5-A]Pyrazine-7(8H)-Carboxylate
CAS No.	374795-76-3
Molecular Formula	C11H17N3O2
Molecular Weight	223.27 g/mol
Synonyms	7-Boc-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine; tert-Butyl 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-7-carboxylate; 5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester; Imidazo[1,5-a]pyrazine-7(8H)-carboxylic acid, 5,6-dihydro-, 1,1-dimethylethyl ester; BOC-7,8-Dihydro-5H-imidazo[1,5-a]pyrazine-7-carboxylate; 374795-76-3; Boc-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 5,6-Dihydroimidazo[1,5-A]Pyrazine-7(8H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.