Description

1-Piperidinecarboxylic Acid, 4-(3-Ethoxy-3-Oxo-1-Propyn-1-Yl)-4-Hydroxy-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is valued for its unique molecular scaffold, which incorporates a protected carboxylic acid, a hydroxyl group, and an ethoxy-oxo-propynyl moiety, making it a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its functionalized piperidine core.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides or herbicides.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-(3-Ethoxy-3-Oxo-1-Propyn-1-Yl)-4-Hydroxy-, 1,1-Dimethylethyl Ester
CAS No.	374794-90-8
Molecular Formula	C15H23NO5
Molecular Weight	297.35 g/mol
Synonyms	tert-Butyl 4-hydroxy-4-(3-ethoxy-3-oxoprop-1-yn-1-yl)piperidine-1-carboxylate; 1-Boc-4-hydroxy-4-(3-ethoxy-3-oxo-1-propynyl)piperidine; 4-(3-Ethoxy-3-oxoprop-1-yn-1-yl)-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-hydroxy-4-(3-ethoxy-3-oxo-1-propynyl)piperidine; Boc-4-hydroxy-4-(3-ethoxy-3-oxopropynyl)piperidine; 4-Hydroxy-4-(3-ethoxy-3-oxo-1-propynyl)piperidine-1-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 4-(3-Ethoxy-3-Oxo-1-Propyn-1-Yl)-4-Hydroxy-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.