Description

3-Nitro-2-Piperazin-1-Ylbenzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzoic acid core substituted with nitro and piperazinyl groups. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development, particularly for candidates targeting central nervous system (CNS) disorders and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, especially in medicinal chemistry programs.
• API Synthesis: Used as a building block for constructing complex molecules in the development of Active Pharmaceutical Ingredients (APIs).
• Chemical Research: Serves as a valuable reagent in academic and industrial laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Bioconjugation & Probe Development: The functional groups present make it suitable for creating chemical probes or for bioconjugation applications in biochemical research.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of target pharmaceutical compounds.

Basic Information

Item	Details
Product Name	3-Nitro-2-Piperazin-1-Ylbenzoic Acid
CAS No.	374063-89-5
Molecular Formula	C11H13N3O4
Molecular Weight	251.24 g/mol
Synonyms	2-(1-Piperazinyl)-3-nitrobenzoic acid; 3-Nitro-2-(piperazin-1-yl)benzoic acid; Benzoic acid, 3-nitro-2-(1-piperazinyl)-; 374063-89-5; 3-Nitro-2-piperazin-1-yl-benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Nitro-2-Piperazin-1-Ylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and pharmaceutical development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.