Description

3-(2-Oxo-Ethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for research and development chemists seeking to construct complex nitrogen-containing heterocycles with precise stereochemistry. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of piperidine-based active pharmaceutical ingredients (APIs), including potential central nervous system (CNS) drugs, analgesics, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate the piperidine scaffold for enhanced biological activity.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands used in enantioselective synthesis and catalysis.
• Material Science Research: Investigated as a monomer or functional additive in the development of specialty polymers with tailored properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) and research institutions for custom synthesis projects and library generation.

Basic Information

Product Name	3-(2-Oxo-Ethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	372159-76-7
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	1-Boc-3-(2-oxoethyl)piperidine; tert-Butyl 3-(2-oxoethyl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-(2-oxoethyl)piperidine; 3-(2-Oxoethyl)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-3-(2-oxoethyl)piperidine; 1-N-Boc-3-(2-oxoethyl)piperidine; Piperidine-1-carboxylic acid, 3-(2-oxoethyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 3-(2-Oxo-Ethyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GLP (Good Laboratory Practice) and cGMP (current Good Manufacturing Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.