Description

(-)-Variabilin is a specific enantiomer of the natural product variabilin, a bioactive compound originally isolated from marine sponges. This high-purity chiral molecule is of significant interest for advanced research and development in medicinal chemistry and pharmacology. It serves as a critical building block and reference standard for scientists in pharmaceutical, biotechnology, and academic institutions exploring novel therapeutic agents.

Application

• Pharmaceutical Research & Development: As a key chiral intermediate or pharmacophore in the synthesis of novel drug candidates targeting various diseases.
• Medicinal Chemistry Studies: Used as a reference standard or lead compound for structure-activity relationship (SAR) studies and bioactivity screening.
• Biochemical Research: Investigation of specific biological pathways and mechanisms of action due to its inherent bioactive properties.
• Academic & Institutional Research: Serves as a pure chemical entity for fundamental studies in organic synthesis, natural product chemistry, and chemical biology.
• High-Purity Reference Standard: Qualification and calibration of analytical methods (e.g., HPLC, Chiral Analysis) in quality control laboratories.

Basic Information

Product Name	(-)-Variabilin
CAS No.	370102-93-5
Molecular Formula	C21H22O3
Molecular Weight	322.40 g/mol
Synonyms	(3aS,4S,9bS)-4-(4-Hydroxyphenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-3,8(9H)-dione; (-)-Variabilin; L-Variabilin; Variabilin enantiomer; Marine sponge metabolite
EINECS	Contact for details

Quality Control

Our (-)-Variabilin is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.