Description

1,4-Di-Boc-2-Piperazineacetic Acid is a high-purity, protected piperazine derivative widely used as a critical building block in organic synthesis. Its primary value lies in providing a reactive carboxylic acid handle on a Boc-protected piperazine scaffold, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and protease inhibitor research.
• Peptidomimetic Chemistry: Serves as a crucial component for constructing peptide-like structures with enhanced metabolic stability.
• Ligand Synthesis: Used in the preparation of chelating agents and ligands for catalysis and medicinal chemistry applications.
• Chemical Biology Probes: Acts as a versatile scaffold for creating tool compounds and probes to study biological pathways.
• Agrochemical Development: Intermediate in the synthesis of advanced crop protection agents and herbicides.
• Custom Synthesis: A foundational material for contract research and manufacturing organizations (CROs/CMOs) performing bespoke chemical synthesis.

Basic Information

Product Name	1,4-Di-Boc-2-Piperazineacetic Acid
CAS No.	368442-00-6
Molecular Formula	C16H28N2O6
Molecular Weight	344.41 g/mol
Synonyms	1,4-Di-tert-butyl 2-(carboxymethyl)piperazine-1,4-dicarboxylate; 2-(1,4-Di-Boc-piperazin-2-yl)acetic Acid; 1,4-Bis(tert-butoxycarbonyl)-2-piperazineacetic Acid; 2-Piperazineacetic Acid, 1,4-Bis[(1,1-dimethylethoxy)carbonyl]-; 1,4-Di-Boc-piperazine-2-acetic Acid; Di-Boc-piperazineacetic Acid; Boc-Pip(Boc)-OH
EINECS	Contact for details

Quality Control

Our 1,4-Di-Boc-2-Piperazineacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if opened, and allow it to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.