Description

4-(2-Chloro-4-Fluorophenoxy)Piperidine is a high-purity, advanced pharmaceutical intermediate with the CAS number 367501-07-3. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is essential for research institutions and manufacturers in the pharmaceutical and agrochemical industries seeking to develop novel therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• API Manufacturing: Employed in the scaled-up production of specific active pharmaceutical ingredients requiring the piperidine-phenoxy structural motif.
• Ligand and Catalyst Development: Potential use in creating specialized ligands for catalytic processes or as a component in organocatalysts.

Basic Information

Product Name	4-(2-Chloro-4-Fluorophenoxy)Piperidine
CAS No.	367501-07-3
Molecular Formula	C11H13ClFNO
Molecular Weight	229.68 g/mol
Synonyms	4-(2-Chloro-4-fluorophenoxy)piperidine; Piperidine, 4-[(2-chloro-4-fluorophenoxy)]-; 2-Chloro-4-fluorophenyl piperidin-4-yl ether; 4-(2-Chloro-4-fluorophenoxy)piperidine hydrochloride (salt form); CAS 367501-07-3
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-4-Fluorophenoxy)Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.