Description

Bicyclo[2.2.1]Heptan-2-Ol, 2-(2-Aminoethyl)-1,3,3-Trimethyl-, (1R,2R,4S)- (9Ci) is a high-purity, stereochemically defined chiral amine-alcohol building block. This compound is valued for its rigid bicyclic framework and dual functional groups, which enable precise molecular construction in advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric catalysis and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize sophisticated chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex natural products, agrochemicals, and specialty materials with defined stereochemistry.
• Academic & Industrial Research: Employed in methodological studies and process chemistry development for new synthetic routes.
• Material Science: Potential monomer or additive for creating polymers with specific structural or optical properties.

Basic Information

Product Name	Bicyclo[2.2.1]Heptan-2-Ol, 2-(2-Aminoethyl)-1,3,3-Trimethyl-, (1R,2R,4S)- (9Ci)
CAS No.	366014-01-9
Molecular Formula	C12H23NO
Molecular Weight	197.32 g/mol
Synonyms	(1R,2R,4S)-2-(2-Aminoethyl)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol; 2-Norbornanemethanol, 2-(2-aminoethyl)-1,3,3-trimethyl-, (1R,2R,4S)-; (1R,2R,4S)-1,3,3-Trimethyl-2-(2-aminoethyl)bicyclo[2.2.1]heptan-2-ol; endo-2-(2-Aminoethyl)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol (stereospecific); Chiral norbornane amino-alcohol derivative
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Every lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and easily oxidized nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1R,2R,4S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.