Description

1,3-Cyclobutanedicarboxaldehyde, 2,2-Dimethyl-, (1R,3R)-Rel- (9Ci) is a high-purity, stereochemically defined cyclobutane derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its rigid, functionalized structure, which is essential for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its stereochemistry can influence biological activity and environmental selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require rigid, alicyclic components.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, enabling new routes to complex, stereodefined carbocycles.

Basic Information

Product Name	1,3-Cyclobutanedicarboxaldehyde, 2,2-Dimethyl-, (1R,3R)-Rel- (9Ci)
CAS No.	364728-44-9
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	(1R,3R)-rel-2,2-Dimethyl-1,3-cyclobutanedicarboxaldehyde; (rel-(1R,3R))-2,2-Dimethyl-1,3-cyclobutanedicarbaldehyde; 2,2-Dimethyl-1,3-cyclobutanedicarboxaldehyde, (1R,3R)-rel-; Chiral 2,2-Dimethylcyclobutane-1,3-dicarbaldehyde; Cyclobutane-1,3-dicarboxaldehyde, 2,2-dimethyl-, (1R,3R)-rel-
EINECS	Contact for details

Quality Control

Our 1,3-Cyclobutanedicarboxaldehyde, 2,2-Dimethyl-, (1R,3R)-Rel- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, enantiomeric excess, and impurity profiles. Our quality system is designed to support cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.