Description

Pyrrolidine, 1-[[(2R)-1-Methyl-2-Pyrrolidinyl]Carbonyl]- (9Ci) is a high-purity, stereochemically defined pyrrolidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex alkaloids or receptor-targeted compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in drug discovery programs aimed at identifying novel therapeutic candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Alkaloid Synthesis: Serves as a foundational structure for the total or semi-synthesis of complex natural products containing pyrrolidine or pyrrolidinone motifs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry: Investigated for scalable routes in the pilot and commercial-scale manufacturing of specialty fine chemicals.

Basic Information

Product Name	Pyrrolidine, 1-[[(2R)-1-Methyl-2-Pyrrolidinyl]Carbonyl]- (9Ci)
CAS No.	364367-05-5
Molecular Formula	C10H18N2O
Molecular Weight	182.26 g/mol
Synonyms	1-[(2R)-1-Methyl-2-pyrrolidinylcarbonyl]pyrrolidine; (R)-1-(1-Methylpyrrolidine-2-carbonyl)pyrrolidine; (R)-N-(1-Methylpyrrolidin-2-yl)pyrrolidine-1-carboxamide; 364367-05-5; UNII-2V7R3K9T6W; 2V7R3K9T6W
EINECS	Contact for details

Quality Control

Our Pyrrolidine, 1-[[(2R)-1-Methyl-2-Pyrrolidinyl]Carbonyl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.