Description

4-[(tert-Butoxy)Carbonyl]-1-(2-Carboxyethyl)Piperazin-1-Ium Chloride is a high-purity, protected piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and sophisticated intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized piperazine scaffolds.
• Peptide Mimetics & Drug Discovery: Used to introduce protected amine and carboxylic acid functionalities for creating peptide analogs and small molecule drug candidates.
• Linker Chemistry: Employed in the construction of bioconjugates, antibody-drug conjugates (ADCs), and polymer-drug conjugates due to its bifunctional reactivity.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides a base-labile protecting group for amines, integral in multi-step synthetic sequences.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Research: Used to synthesize functional monomers and cross-linkers for advanced polymers and smart materials.

Basic Information

Product Name	4-[(tert-Butoxy)Carbonyl]-1-(2-Carboxyethyl)Piperazin-1-Ium Chloride
CAS No.	362690-46-8
Molecular Formula	C12H21ClN2O4
Molecular Weight	292.76 g/mol
Synonyms	1-(2-Carboxyethyl)-4-(tert-butoxycarbonyl)piperazin-1-ium chloride; 1-Carboxyethyl-4-Boc-piperazinium chloride; 4-Boc-1-(2-carboxyethyl)piperazin-1-ium chloride; N-Boc-N'-(2-carboxyethyl)piperazinium chloride; 2-[4-[(2-Methylpropan-2-yl)oxycarbonyl]piperazin-1-ium-1-yl]acetate chloride; (2-{4-[(tert-Butoxy)carbonyl]piperazin-1-ium-1-yl}acetate) chloride; Boc-Pip(Carboxyethyl)-OH chloride
EINECS	Contact for details

Quality Control

Our 4-[(tert-Butoxy)Carbonyl]-1-(2-Carboxyethyl)Piperazin-1-Ium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.