Description

1-(3-Chloropropyl)-Homopiperazine Dihydrochloride Hemi-Hydrate is a high-purity, functionalized piperazine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Serves as a functional monomer or cross-linking agent for specialty polymers with tailored properties.
• Agrochemical Research: Employed in the synthesis of new herbicide and pesticide molecules.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and custom synthesis houses.

Basic Information

Product Name	1-(3-Chloropropyl)-Homopiperazine Dihydrochloride Hemi-Hydrate
CAS No.	362690-42-4
Molecular Formula	C8H18Cl2N2 • 0.5H2O • 2HCl
Molecular Weight	Contact for details
Synonyms	1-(3-Chloropropyl)hexahydro-1H-1,4-diazepine dihydrochloride hemihydrate; Homopiperazine, 1-(3-chloropropyl)-, dihydrochloride, hemihydrate; 1-(3-Chloropropyl)homopiperazine 2HCl 0.5H2O; 1-(3-Chloropropyl)-1,4-diazepane dihydrochloride hemihydrate; 362690-42-4; 1-(3-Chloropropyl)perhydro-1,4-diazepine dihydrochloride hemihydrate
EINECS	Contact for details

Quality Control

Our 1-(3-Chloropropyl)-Homopiperazine Dihydrochloride Hemi-Hydrate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	2.0% - 4.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.