Description

1H-Imidazo[4,5-B]Pyrazin-2-Amine is a high-purity heterocyclic organic compound, identified by CAS NO 361382-81-2, that serves as a critical advanced pharmaceutical intermediate and building block in medicinal chemistry. Its imidazopyrazine core structure is of significant value for the research and development of novel therapeutic agents, particularly in oncology and antiviral applications. This compound is essential for pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting kinase inhibition for cancer therapy.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Biochemical Reagent: Serves as a substrate or inhibitor in enzymatic assays and biochemical research.
• Organic Synthesis: A versatile precursor for constructing fused heterocyclic systems with potential biological activity.
• Agrochemical Development: Investigated as an intermediate for novel pesticides and herbicides due to its heterocyclic scaffold.
• Material Science Research: Explored as a potential ligand or component in the development of organic electronic materials.

Basic Information

Product Name	1H-Imidazo[4,5-B]Pyrazin-2-Amine
CAS No.	361382-81-2
Molecular Formula	C5H4N6
Molecular Weight	148.13 g/mol
Synonyms	2-Amino-1H-imidazo[4,5-b]pyrazine; 1H-Imidazo[4,5-b]pyrazin-2-ylamine; Imidazo[4,5-b]pyrazin-2-amine; 2-Aminoimidazo[4,5-b]pyrazine; 361382-81-2; 2-Amino-1H-imidazo[4,5-b]pyrazine; 1H-Imidazo[4,5-b]pyrazine-2-amine
EINECS	Contact for details

Quality Control

Our 1H-Imidazo[4,5-B]Pyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.