Description

tert-Butyl 4-(3-Aminobenzyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative of significant importance in modern organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical agents and bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of complex heterocyclic compounds and targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Employed to introduce the piperazine moiety into peptide analogs to enhance metabolic stability and bioavailability.
• Ligand Development: Serves as a building block for creating novel ligands for G-protein-coupled receptors (GPCRs) and other biological targets.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and cellular pathways.
• Agrochemical Research: Potential intermediate in the research and development of new crop protection agents and pesticides.

Basic Information

Product Name	tert-Butyl 4-(3-Aminobenzyl)Piperazine-1-Carboxylate
CAS No.	361345-40-6
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	1-Boc-4-(3-aminobenzyl)piperazine; tert-Butyl 4-[(3-aminophenyl)methyl]piperazine-1-carboxylate; 4-(3-Aminobenzyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-aminobenzyl)piperazine; N-Boc-4-(3-aminobenzyl)piperazine; 361345-40-6; 3-((4-(tert-Butoxycarbonyl)piperazin-1-yl)methyl)aniline
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Aminobenzyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with the standards expected for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.