Description

tert-Butyl 4-(2-Methyl-4-Nitrophenyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperazine core and nitrophenyl substituent. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical manufacturers and research organizations engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting the central nervous system.
• API Synthesis: Used in the research and production of Active Pharmaceutical Ingredients (APIs) requiring a functionalized piperazine moiety.
• Medicinal Chemistry R&D: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in pharmaceutical laboratories.
• Organic Synthesis: Utilized in academic and industrial research for constructing nitrogen-containing heterocycles and complex molecular architectures.

Basic Information

Product Name	tert-Butyl 4-(2-Methyl-4-Nitrophenyl)Piperazine-1-Carboxylate
CAS No.	361345-36-0
Molecular Formula	C16H23N3O4
Molecular Weight	321.37 g/mol
Synonyms	1-Boc-4-(2-Methyl-4-nitrophenyl)piperazine; tert-Butyl 4-(2-methyl-4-nitrophenyl)-1-piperazinecarboxylate; 4-(2-Methyl-4-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(2-methyl-4-nitrophenyl)piperazine; BOC-2-Methyl-4-nitrophenylpiperazine; 361345-36-0; N-Boc-4-(2-Methyl-4-nitrophenyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Methyl-4-Nitrophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light) and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.