Description

tert-Butyl 4-(2-Methoxybenzylamino)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a Boc (tert-butoxycarbonyl) group and functionalized with a 2-methoxybenzylamino substituent. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of new therapeutic agents, particularly in the areas of central nervous system (CNS) and receptor-targeted drugs.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• API (Active Pharmaceutical Ingredient) Synthesis: Serves as a crucial building block in multi-step synthetic routes for potential active ingredients.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme and receptor function.
• Custom Synthesis & Scale-Up: Available for custom manufacturing projects, from gram-scale R&D to kilogram-scale pilot production.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	tert-Butyl 4-(2-Methoxybenzylamino)Piperidine-1-Carboxylate
CAS No.	359877-80-8
Molecular Formula	C18H28N2O3
Molecular Weight	320.43 g/mol
Synonyms	1-Boc-4-[(2-Methoxybenzyl)amino]piperidine; 4-[(2-Methoxybenzyl)amino]-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1-(tert-Butoxycarbonyl)-4-[(2-methoxybenzyl)amino]piperidine; N-(2-Methoxybenzyl)-4-amino-1-Boc-piperidine; tert-Butyl 4-[(2-methoxybenzyl)amino]piperidine-1-carboxylate; 4-(2-Methoxybenzylamino)piperidine-1-carboxylic Acid tert-Butyl Ester; Boc-4-(2-Methoxybenzylamino)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Methoxybenzylamino)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acids/organic solvents. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.