Description

Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-7-Hydroxy-3-Methyl-, (3R,7S,8Ar)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its complex fused-ring structure and specific stereochemistry make it an invaluable building block for the development of novel, high-value active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Agrochemical Research: Used as a precursor in the development of new-generation herbicides and fungicides with novel modes of action.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing pyrrolopyrazine-based libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential application in the synthesis of organic semiconductors and ligands for catalytic systems due to its rigid, nitrogen-rich heterocyclic core.
• Bioconjugation Chemistry: The functional groups present can be utilized for developing novel linkers and probes in chemical biology and diagnostic applications.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-7-Hydroxy-3-Methyl-, (3R,7S,8Ar)- (9Ci)
CAS No.	356787-21-8
Molecular Formula	C7H10N2O3
Molecular Weight	170.17 g/mol
Synonyms	(3R,7S,8aR)-Hexahydro-7-hydroxy-3-methyl-pyrrolo[1,2-a]pyrazine-1,4-dione; (3R,7S,8aR)-Hexahydro-7-hydroxy-3-methyl-1H,3H-pyrrolo[1,2-a]pyrazine-1,4-dione; 7-Hydroxy-3-methylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Stereoisomer of Alantrypinone; Chiral Lactam Intermediate; Fused Bicyclic Lactam
EINECS	Contact for details

Quality Control

Our production of Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-7-Hydroxy-3-Methyl-, (3R,7S,8Ar)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques, including chiral HPLC to confirm stereochemical purity and NMR for structural verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to atmospheric moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.