Description

Pyrazinecarboxamide, 6-Fluoro-, 4-Oxide (9Ci) is a specialized heterocyclic compound featuring a fluorinated pyrazine core with a carboxamide group and an N-oxide moiety, offering unique reactivity and electronic properties. This high-purity intermediate is critical for advanced research and development in pharmaceutical chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It serves as a key building block for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate fluorinated heterocyclic structures.

Application

• Pharmaceutical Intermediate: A crucial building block for the research and synthesis of novel drug candidates, especially in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorinated pyrazine structure can enhance biological activity and environmental stability.
• Chemical Synthesis Reagent: Serves as a versatile precursor for further functionalization, enabling the creation of complex molecular libraries for high-throughput screening (HTS).
• Material Science Research: Investigated for potential use in the development of organic electronic materials, ligands for catalysis, and specialty polymers.
• Academic & Institutional R&D: Employed in university and government laboratories for fundamental studies on fluorinated heterocycles and N-oxide chemistry.

Basic Information

Product Name	Pyrazinecarboxamide, 6-Fluoro-, 4-Oxide (9Ci)
CAS No.	356783-48-7
Molecular Formula	C5H4FN3O2
Molecular Weight	157.10 g/mol
Synonyms	6-Fluoropyrazine-2-carboxamide 4-oxide; 6-Fluoropyrazinecarboxamide 1-oxide; 2-Fluoro-5-carbamoylpyrazine 1-oxide; 6-Fluoro-1-oxido-2-pyrazinecarboxamide; 6-Fluoropyrazine-2-carboxylic acid amide N-oxide; 2-Carbamoyl-6-fluoropyrazine 1-oxide; 6-Fluoropyrazine-2-carboxamide N-oxide; 6-Fluoro-2-pyrazinecarboxamide 4-oxide
EINECS	Contact for details

Quality Control

Our Pyrazinecarboxamide, 6-Fluoro-, 4-Oxide (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support custom purity specifications to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.