Description

2-Pyrazinecarbonitrile, 6-Fluoro-3,4-Dihydro-3-Oxo- is a high-purity fluorinated pyrazine derivative, a key synthetic intermediate valued for its reactive nitrile and ketone functional groups. This compound is essential for constructing complex heterocyclic scaffolds in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized heterocyclic compounds used in organic electronic materials and ligands for catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific, complex fluorinated heterocycles.

Basic Information

Product Name	2-Pyrazinecarbonitrile, 6-Fluoro-3,4-Dihydro-3-Oxo-
CAS No.	356783-31-8
Molecular Formula	C6H4FN3O
Molecular Weight	153.11 g/mol
Synonyms	6-Fluoro-3-oxo-3,4-dihydro-2-pyrazinecarbonitrile; 6-Fluoro-3,4-dihydro-3-oxopyrazine-2-carbonitrile; 6-Fluoro-2-cyano-3(2H)-pyrazinone; 6-Fluoro-3-oxo-3,4-dihydropyrazine-2-carbonitrile; 2-Cyano-6-fluoro-3(2H)-pyrazinone; 356783-31-8; 6-Fluoro-3-oxo-3,4-dihydro-pyrazine-2-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Pyrazinecarbonitrile, 6-Fluoro-3,4-Dihydro-3-Oxo- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent batch-to-batch quality suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.