Description

Pyrazinecarboxamide, 3,6-Difluoro- (9Ci) is a high-value fluorinated heterocyclic building block, distinguished by its unique substitution pattern. This compound is critical for introducing the pyrazine pharmacophore with fluorine atoms into target molecules, enabling fine-tuning of electronic properties, lipophilicity, and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the difluoropyrazine moiety enhances bioactivity.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, organic semiconductors, and fluorinated polymers.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital building block for fine chemical suppliers offering bespoke synthesis services to global clients.

Basic Information

Product Name	Pyrazinecarboxamide, 3,6-Difluoro- (9Ci)
CAS No.	356783-29-4
Molecular Formula	C5H3F2N3O
Molecular Weight	159.10 g/mol
Synonyms	3,6-Difluoropyrazine-2-carboxamide; 2-Pyrazinecarboxamide, 3,6-difluoro-; 3,6-Difluoropyrazinecarboxamide; 3,6-Difluoro-2-pyrazinecarboxamide; 3,6-Difluoro-2-carbamoylpyrazine; 356783-29-4; AI3-63231; CTK8G0186
EINECS	Contact for details

Quality Control

Every batch of 3,6-Difluoropyrazine-2-carboxamide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.