Description

3,6-Difluoropyrazine-2-Carbonitrile is a high-purity fluorinated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine atoms and a nitrile group, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and electronic materials where the pyrazine core contributes to specific optical or conductive properties.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand Synthesis: Useful for preparing novel ligands in catalysis and coordination chemistry.

Basic Information

Product Name	3,6-Difluoropyrazine-2-Carbonitrile
CAS No.	356783-28-3
Molecular Formula	C5HF2N3
Molecular Weight	141.08 g/mol
Synonyms	2,5-Difluoropyrazine-3-carbonitrile; 2-Cyano-3,6-difluoropyrazine; 3,6-Difluoropyrazinecarbonitrile; 3,6-Difluoro-2-pyrazinecarbonitrile; 2-Pyrazinecarbonitrile, 3,6-difluoro-
EINECS	Contact for details

Quality Control

Our 3,6-Difluoropyrazine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that batch. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.