Description

Methyl 6-Fluoro-3-Hydroxypyrazine-2-Carboxylate is a high-purity fluorinated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a hydroxyl group on the pyrazine core, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a starting material for the synthesis of specialized ligands, fluorinated heterocycles, and functionalized polymers.
• Chemical Biology Probe Development: Utilized in creating molecular probes and tags for studying biological processes due to its modifiable functional groups.
• Academic & Contract Research: Essential for methodological research in organic chemistry, including studies on fluorination reactions and heterocyclic chemistry.

Basic Information

Product Name	Methyl 6-Fluoro-3-Hydroxypyrazine-2-Carboxylate
CAS No.	356783-27-2
Molecular Formula	C6H5FN2O3
Molecular Weight	172.11 g/mol
Synonyms	6-Fluoro-3-hydroxypyrazine-2-carboxylic acid methyl ester; Methyl 6-fluoro-3-oxo-3,4-dihydropyrazine-2-carboxylate; 2-Pyrazinecarboxylic acid, 6-fluoro-3-hydroxy-, methyl ester; 6-Fluoro-3-hydroxy-2-pyrazinecarboxylic acid methyl ester; MFHPC
EINECS	Contact for details

Quality Control

Our Methyl 6-Fluoro-3-Hydroxypyrazine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.