Description

3,6-Dichloropyrazine-2-Carbonitrile is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering distinct sites for nucleophilic aromatic substitution and cyano group transformations, enabling the rapid construction of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of biologically active pyrazine derivatives, including potential kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyrazine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient aromatic system.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: Fundamental research reagent for exploring new heterocyclic chemistry and reaction methodologies in university and corporate laboratories.

Basic Information

Product Name	3,6-Dichloropyrazine-2-Carbonitrile
CAS No.	356783-16-9
Molecular Formula	C5HCl2N3
Molecular Weight	173.99 g/mol
Synonyms	2,5-Dichloropyrazine-3-carbonitrile; 3,6-Dichloro-2-cyanopyrazine; 2,5-Dichloro-3-cyanopyrazine; Pyrazine-2-carbonitrile, 3,6-dichloro-; 3,6-Dichloro-2-pyrazinecarbonitrile; 2-Cyano-3,6-dichloropyrazine
EINECS	Contact for details

Quality Control

Our 3,6-Dichloropyrazine-2-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and lot-to-lot consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.