Description

Benzeneacetic Acid, 2-(Chlorocarbonyl)-, Methyl Ester (9Ci) is a specialized organic ester building block of significant interest in advanced synthetic chemistry. Its core value lies in its bifunctional reactivity, featuring both an acid chloride and an ester group, which makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel compounds. Its precise structure enables controlled derivatization, supporting innovation in drug discovery and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in constructing complex ester and amide linkages.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators requiring specific chlorocarbonyl chemistry.
• Organic Synthesis Reagent: Serves as a versatile acylating agent in academic and industrial laboratories for introducing the phenylacetic acid derivative moiety into target molecules.
• Peptide Mimetic Research: Employed in the development of peptide analogs and bioisosteres due to its reactive functional groups that can mimic natural amino acid side chains.
• Material Science Precursor: Potential intermediate in the synthesis of specialized monomers for polymers, coatings, or liquid crystals with tailored properties.
• Chemical Biology Probes: Useful for creating labeled compounds or affinity probes for studying biological targets and pathways.

Basic Information

Product Name	Benzeneacetic Acid, 2-(Chlorocarbonyl)-, Methyl Ester (9Ci)
CAS No.	356558-47-9
Molecular Formula	C10H9ClO3
Molecular Weight	212.63 g/mol
Synonyms	2-(Chlorocarbonyl)phenylacetic acid methyl ester; Methyl 2-(chlorocarbonyl)phenylacetate; Methyl (2-chloro-2-oxoethyl)benzoate; Methyl 2-(chloroformyl)phenylacetate; α-(Methoxycarbonyl)benzeneacetyl chloride; Benzeneacetic acid, α-(chlorocarbonyl)-, methyl ester; (2-Chloro-2-oxoethyl)benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 2-(Chlorocarbonyl)-, Methyl Ester is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical characterization, including purity assay and identity confirmation. Certificates of Analysis (COA) detailing specific results for all tested parameters are provided and available upon request, supporting compliance in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain purity. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.