Description

(2E)-4-[4-(Diphenylmethyl)Piperazin-1-Yl]-4-Oxobut-2-Enoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific molecular architecture. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where precise chemical structure is paramount. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of proprietary drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex piperazine and diphenylmethyl-containing molecular frameworks.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within R&D laboratories.
• Process Development: Used for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API production.

Basic Information

Product Name	(2E)-4-[4-(Diphenylmethyl)Piperazin-1-Yl]-4-Oxobut-2-Enoic Acid
CAS No.	353276-06-9
Molecular Formula	C21H22N2O3
Molecular Weight	350.42 g/mol
Synonyms	4-[4-(Diphenylmethyl)-1-piperazinyl]-4-oxo-2-butenoic acid; (E)-4-[4-(Benzhydryl)piperazin-1-yl]-4-oxobut-2-enoic acid; 4-[4-(Diphenylmethyl)piperazin-1-yl]-4-oxobut-2-enoic acid; 353276-06-9; But-2-enoic acid, 4-[4-(diphenylmethyl)-1-piperazinyl]-4-oxo-, (2E)-; (2E)-4-[4-(Diphenylmethyl)-1-piperazinyl]-4-oxo-2-butenoic acid
EINECS	Contact for details

Quality Control

Our (2E)-4-[4-(Diphenylmethyl)Piperazin-1-Yl]-4-Oxobut-2-Enoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.