Description

1-(2-Chloro-Benzoyl)-Piperidine-4-Carboxylic Acid is a high-purity, versatile chemical intermediate of significant importance in advanced organic synthesis. Its unique piperidine-carboxylic acid scaffold, functionalized with a chlorobenzoyl group, makes it a critical building block for constructing complex molecular architectures. This compound is primarily sought after by research and development teams within the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly those targeting the central nervous system (CNS) or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its halogenated aromatic structure.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic Research: Utilized in university and institutional laboratories for studying organic reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	1-(2-Chloro-Benzoyl)-Piperidine-4-Carboxylic Acid
CAS No.	352673-16-6
Molecular Formula	C13H14ClNO3
Molecular Weight	267.71 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-[(2-chlorophenyl)carbonyl]-; 1-(2-Chlorobenzoyl)piperidine-4-carboxylic acid; 1-(2-Chlorobenzoyl)-4-piperidinecarboxylic acid; 2-Chloro-N-(4-carboxypiperidin-1-yl)benzamide; Piperidine-4-carboxylic acid, 1-(2-chlorobenzoyl)-; 352673-16-6; 1-(2-Chloro-benzoyl)-piperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-Benzoyl)-Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.